Center for Medical Genetics Ltd – Specialized Center for Prenatal Diagnosis
Karel Čutka, MD, David Čutka, MD, Novohradská 68/1806, České Budějovice

Invasive prenatal testing – amniocentesis, chorionic villus sampling (CVS)

Main indications - reasons:

• positive screening for congenital anomalies (mother’s blood testing eventually followed by ultrasound scanning selects women with an increased risk of chromosomal anomalies in a fetus, e.g. Down syndrome)
• need for additional testing for patients with hereditary diseases in the family (e.g. molecular genetics)
• previous pregnancy terminated due to a detection of a congenital anomaly (invasive testing done by patient’s request)
• patient is 35 or more at time of birth (invasive testing done by patient’s request)
• amniotic fluid testing – amniocentesis